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GUARD CELLULAR DEFENSE

Your defense system was not built for the pace of a modern week. Short sleep, chronic stress, ultra-processed food, and hard training all raise the everyday oxidative stress your cells have to manage. Aging does the same, year over year. None of this is a crisis. It is simply more asked of a system that runs best when it has support.

0% more oxidative stress after six weeks of short sleep Short sleep and chronic stress Scientific Reports, 2023
0% more oxidized glutathione right after hard exercise Hard training and busy days Am. J. Physiology, 1992
0 the age your body's frontline antioxidant defenses start to fade Aging, year over year Clinical Biochemistry, 1997

Your body already has a master defense switch.

It's called Nrf2. Deep inside every cell sits a control switch called Nrf2, your body's own master regulatory system for defense against everyday oxidative stress. It is a system you were born with, working quietly in the background every day.

When activated, it turns on your body's own defense machinery.

Nrf2 activation upregulates antioxidant production, triggers cellular repair mechanisms, and turns on the transcription of over 200 cytoprotective genes, including Phase II detoxification enzymes that can convert fat-soluble toxins into water-soluble compounds your body can excrete.

0+ protective genes switched on.

This is not about masking symptoms. When Nrf2 is switched on, your cells strengthen the defenses they already have: antioxidant enzymes that neutralize free radicals, repair proteins that mend daily wear, and your Phase II defense system. One switch, a coordinated whole-cell response.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Glucoraphanin

100 mg from broccoli seed extract

The most stable and clinically studied precursor to sulforaphane. The same form used in the landmark Egner et al. human detoxification trials at Johns Hopkins.

Egner et al. 2014

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Myrosinase

75 mg from mustard seed powder

The enzyme that turns glucoraphanin into active sulforaphane, the most potent natural activator of your body's Nrf2 defense pathway. Without it, conversion can drop into the low single digits. By pairing it with mustard seed myrosinase, Guard SRF will target roughly 40% conversion to active sulforaphane.

Mastaloudis et al. 2026

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Vitamin C

100 mg ascorbic acid

Ascorbic acid, included as an enzymatic cofactor that supports the myrosinase conversion step. 100mg ensures the optimal conversion environment for maximum sulforaphane yield.

Mastaloudis et al. 2026

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

For the people who read the studies.

Sulforaphane is one of the most studied natural compounds in the world, with more than 1,900 published studies and dozens of registered human trials from major research institutions. It is an indirect antioxidant: it amplifies the defenses you already have rather than replacing them. In a human study, sulforaphane raised blood glutathione, the body's master antioxidant, by 32%.

Sedlak et al. 2018

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

The industry has a transparency problem.

Across the category, labels print "sulforaphane glucosinolate," which is actually glucoraphanin, the precursor, not sulforaphane itself. Most supplements skip the myrosinase enzyme entirely, leaving as little as 5% bioavailability, and independent testing has shown some products deliver a fraction of what is on the label. Almost no sulforaphane brand carries third-party certification. Guard SRF will disclose every ingredient and every dose, will be third-party tested, and will publish a Certificate of Analysis for every batch.

Your defenses work everywhere, including in your skin.

Beauty really does start from within. Sulforaphane supports your skin's own antioxidant defenses, the ones it already makes to look after itself. In a small randomized study of 18 people over about 10 days, oral glucoraphanin raised the expression of the skin's own NQO1 defense enzyme by roughly three times, and lowered two inflammatory markers the researchers measured. This is early, small, short-duration human data.

Chien & Fahey 2025

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

~3×

your skin's own NQO1 defense enzyme

18 people · 10 days · oral glucoraphanin

Early, small, short-duration human data.

Chien & Fahey 2025

We built Guard because we couldn't find what we were looking for.

Every sulforaphane supplement we tested was either underdosed, untested, or hiding behind proprietary blends. So we made one that isn't.

We are testing it on ourselves first. Every batch will be third-party tested. Every certificate of analysis will be published.

No proprietary blends. No filler. No mystery.

We are not here to sell you a fight against the outside world. We are here to help your own defenses stay strong as the years add up.

Frequently Asked

Sulforaphane is the most potent natural activator of the Nrf2 pathway, your cell's master switch for defense. Discovered at Johns Hopkins in the 1990s, it activates transcription of over 200 cytoprotective genes, including Phase II detoxification enzymes.

Most sulforaphane supplements contain only 25-30mg of glucoraphanin without the myrosinase enzyme needed to convert it. Without myrosinase, bioavailability drops to as low as 5%. Guard SRF will deliver 100mg of glucoraphanin co-formulated with 75mg of mustard seed myrosinase and 100mg of vitamin C as an enzymatic cofactor, achieving up to 40% conversion to active sulforaphane.

Sulforaphane has been studied extensively in human clinical trials with an excellent safety profile. Guard SRF will use well-studied ingredients at transparent doses. As with any supplement, consult your healthcare provider if you are pregnant, nursing, or taking medications.

SRF is currently in development. Join the waitlist to be the first to know when we launch, and to lock in founding member pricing and first access.

Guard is subscription-first (30 capsules, 30-day supply). Founding members from the waitlist get first access and preferred pricing. Your first order will ship in a premium glass bottle welcome kit. Refills will ship in compostable pouches.

Every batch of SRF will be third-party tested, and its certificate of analysis (COA) published. We have not produced our first batch yet, so there is nothing to show today. See our Lab Results page for the standing commitment. Transparency is not a marketing angle for us. It is the foundation.

Fresh broccoli sprouts offer the highest sulforaphane bioavailability (30-40%), but come with real trade-offs: a 3-5 day growing cycle, twice-daily rinsing, mold risk, about one week of shelf life, and no dose standardization. Guard SRF will deliver a transparent, well-studied dose in a stable, convenient capsule with co-formulated myrosinase for consistent conversion every time.

Your skin runs on the same defense system as the rest of your body, it makes its own antioxidant enzymes to protect itself. Sulforaphane supports those built-in defenses from within, rather than sitting on the surface like a topical. The early human evidence is in the Wellness section above, small and short-duration, and we present it as exactly that.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Your cells have a guardian now.

Join the waitlist for founding member pricing and first access.

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